IJMS | Free Full-Text | Therapeutic Targeting of Alternative RNA Splicing in Gastrointestinal Malignancies and Other Cancers | HTML
The catalytic spliceosome inhibitor E7107 induces IR and has potent... | Download Scientific Diagram
Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma | bioRxiv
SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia
A Comprehensive Overview of Structure‐Activity Relationships of Small‐Molecule Splicing Modulators Targeting SF3B1 as Anticancer Agents - Zhang - 2020 - ChemMedChem - Wiley Online Library
RCSB PDB - 5ZYA: SF3b spliceosomal complex bound to E7107
E7107
Dysregulated Alternative Splicing Landscape Identifies Intron Retention as a Hallmark and Spliceosome as a Therapeutic Vulnerability in Aggressive Prostate Cancer | bioRxiv
Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma - ScienceDirect
SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia | Leukemia
Scalable Synthesis of 17S-FD-895 Expands the Structural Understanding of Splice Modulatory Activity - ScienceDirect
RCSB PDB - 5ZYA: SF3b spliceosomal complex bound to E7107
A phase I, open-label, single-arm, dose-escalation study of E7107, a precursor messenger ribonucleic acid (pre-mRNA) splicesome inhibitor administered intravenously on days 1 and 8 every 21 days to patients with solid tumors
Cancers | Free Full-Text | Somatic Mutations in Core Spliceosome Components Promote Tumorigenesis and Generate an Exploitable Vulnerability in Human Cancer | HTML
Combination of splicing modulator E7107 with BCLxL inhibitors induces... | Download Scientific Diagram
E7107
Unii-R60dzx1E2N | C40H66N2O9 - PubChem
2018 Bone Marrow Failure Highlight - A Novel Therapy for Targeting Acquired Bone Marrow Failure Diseases , Bone Marrow Failure Research Program, Congressionally Directed Medical Research Programs
Frontiers | Innovative Therapeutic and Delivery Approaches Using Nanotechnology to Correct Splicing Defects Underlying Disease | Genetics
IJMS | Free Full-Text | Therapeutic Targeting of Alternative RNA Splicing in Gastrointestinal Malignancies and Other Cancers | HTML
The catalytic spliceosome inhibitor E7107 induces IR and has potent... | Download Scientific Diagram
Inhibition and modulation of the effect of E7107 on global splicing... | Download Scientific Diagram
E7107 | CAS#630100-90-2 | spliceosome inhibitor | MedKoo
Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds - ScienceDirect
Splicing modulators: on the way from nature to clinic | The Journal of Antibiotics
Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma - ScienceDirect
